Search on: RECEPTOR, EPIDERMAL GROWTH FACTOR 
Descriptors Found: 1
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Descriptor English:   Receptor, Epidermal Growth Factor 
Descriptor Spanish:   Receptor del Factor de Crecimiento Epidérmico 
Descriptor Portuguese:   Receptor do Fator de Crescimento Epidérmico 
Synonyms English:   Epidermal Growth Factor Receptor Kinase
Proto-oncogene c-ErbB-1 Protein
Receptor, ErbB-1
Resceptor Tyrosine-protein Kinase erbB-1
Epidermal Growth Factor Receptor Protein Tyrosine Kinase
ErbB-1 Receptor
Protein, Proto-oncogene c-ErbB-1
Proto oncogene c ErbB 1 Protein
Proto-Oncogene Protein, erbB-1
Receptor, ErbB 1
Receptor, TGF alpha
Receptor, Transforming Growth Factor alpha
Resceptor Tyrosine protein Kinase erbB 1
c erbB 1 Protein
c-ErbB-1 Protein, Proto-oncogene
erbB 1 Proto Oncogene Protein
c-erbB-1 Protein
EGF Receptor
Epidermal Growth Factor Receptor
Receptor, Transforming-Growth Factor alpha
Urogastrone Receptor
Receptor, TGF-alpha
Receptor, Urogastrone
Transforming Growth Factor alpha Receptor
TGF-alpha Receptor
erbB-1 Proto-Oncogene Protein
Epidermal Growth Factor Receptor Protein-Tyrosine Kinase
Receptor, EGF  
Tree Number:   D08.811.913.696.620.682.725.400.009.300
D12.776.543.750.630.009.300
D12.776.543.750.750.360.300
D12.776.543.750.750.400.074.300
Definition English:   A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. 
See Related English:   Genes, erbB-1
 
History Note English:   2000(1987); for EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE use RECEPTOR, EPIDERMAL GROWTH FACTOR 1994-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24479 
Unique Identifier:   D011958 

Occurrence in VHL: 		 

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